Animal experiments under fire for poor design

Key NASA lab under fire for animal care practices.

C. Thomas Caskey Dennis W. Choi John M. Coffin F. Fleming Crim Paul J. Crutzen James E. Dahlberg Robert Desimone Bruce F. Eldridge Paul T. Englund Richard G. Fairbanks Douglas T. Fearon Harry A. Fozzard Klaus Friedrich Theodore H. Geballe Roger 1. M. Glass Stephen P. Goff Peter N. Goodfellow Corey S. Goodman Ira Herskowitz Eric F. Johnson Stephen M. Kosslyn Michael LaBarbera Nicole Le Douarin C...

Systematic reviews of animal experiments demonstrate poor human utility

The assumption that animal models are reasonably predictive of human outcomes provides the basis for their widespread use in toxicity testing, and in biomedical research aimed at developing cures for human diseases. To investigate the validity of this assumption, the comprehensive 'Scopus' biomedical bibliographic databases were searched for published systematic reviews of the human clinical or...

An Implantable Retinal Stimulator Design for Long-term Animal Experiments

an implantable stimulator, which provides continuous electrical stimulation and an external component, which provides preset stimulation parameters and power to the implanted stimulator via a paired RF (radio frequency) coil. A rechargeable internal battery and a parameter memory part were introduced to the implantable stimulator to avoid use of the external component during the stimulation cyc...

IIIT Hyderabad’s CLIR experiments for FIRE-2008

This paper discourses our CLIR experiments performed for the FIRE workshop. We had submitted our runs for Adhoc monolingual document retrieval in Hindi and English, and Ad-hoc cross-lingual document retrieval from Hindi to English, and English to Hindi. In this paper, we describe our English to Hindi and Hindi to English CLIR systems and the experiments conducted on them using the FIRE2008 data...

Failure design of high-rise concrete panels under fire loading